John McAfee Out of Hospital, Back in Cell

Software millionaire John McAfee has been returned to an immigration detention cell in Guatemala after being rushed to a Guatemala City hospital via ambulance.

McAfee, 67 -- who soon may be deported back to Belize, where authorities want to question him about the shooting death of his neighbor -- was reportedly found prostrate on the floor of his cell and unresponsive.

He was wheeled into the hospital on a gurney. Photographers followed in pursuit right into the emergency room, but as emergency workers eased McAfee's limp body from the gurney and onto a bed and began to remove his suit, he suddenly spoke up, saying, "Please, not in front of the press."

Earlier today, McAfee had complained of chest pains, raising concerns he might be having a heart attack.

However, that did not appear to be the case. Hours after his emergency, hospital officials sent McAfee back to the detention center, telling ABC News they found no reason to keep him overnight.

In a phone interview overnight, McAfee told ABC News, "I simply passed out, everything went black."

He said he hit his head on the floor when he collapsed. McAfee explained that for the past 48 hours he hasn't eaten and had very little to drink.

McAfee had been scheduled to be deported to Belize, ABC News has learned. But a judge could stay the ruling if it is determined that McAfee's life is threatened by being in Belizean custody, as McAfee has claimed in the past several weeks.

McAfee's attorneys hope to continue delaying the deportation by appealing to the Guatemala's high court on humanitarian grounds.

Raphael Martinez, a spokesman for the Belize government, said that if McAfee is deported to Belize, he would immediately be handed over to police and detained for up to 48 hours unless charges are brought against him.

"There is more that we know about the investigation, but that remains part of the police work," he said, hinting at possible charges.

He added that a handover by Guatemala would be "the neighborly thing to do."

A spokesman for the U.S. embassy in Guatemala said that "due to privacy considerations," the embassy would "have no comment on the specifics of this situation," but that, "U.S. citizens are subject to the laws of the countries in which they are traveling or residing, and must work within the host countries' legal framework."

Guatemala's National Police/AP Photo

Software Founder Breaks Silence: McAfee Speaks on Murder Allegations Watch Video

John McAfee Interview: Software Mogul Leaves Belize Watch Video

Just hours before McAfee's arrest, he told ABC News in an exclusive interview Wednesday he would be seeking asylum in Guatemala. McAfee was arrested by the Central American country's immigration police and not the national police, said his attorney, who was confident his client would be released within hours.

"Thank God I am in a place where there is some sanity," said McAfee before his arrest. "I chose Guatemala carefully."

McAfee said that in Guatemala, the locals aren't surprised when he says the Belizean government is out to kill him.

"Instead of going, 'You're crazy,' they go, 'Yeah, of course they are,'" he said. "It's like, finally, I understand people who understand the system here."

But McAfee added he has not ruled out moving back to the United States, where he made his fortune as the inventor of anti-virus software, and that despite losing much of his fortune he still has more money than he could ever spend.

In his interview with ABC News, a jittery, animated but candid McAfee called the media's representation of him a "nightmare that is about to explode," and said he's prepared to prove his sanity.

McAfee has been on the run from police in Belize since the Nov. 10 murder of his neighbor, fellow American expatriate Greg Faull.

During his three-week journey, said McAfee, he disguised himself as handicapped, dyed his hair seven times and hid in many different places during his three-week journey.

He dismissed accounts of erratic behavior and reports that he had been using the synthetic drug bath salts. He said he had never used the drug, and said statements that he had were part of an elaborate prank.

Investigators said that McAfee was not a suspect in the death of the former developer, who was found shot in the head in his house on the resort island of San Pedro, but that they wanted to question him.

McAfee told ABC News that the poisoning death of his dogs and the murder just hours later of Faull, who had complained about his dogs, was a coincidence.

McAfee has been hiding from police ever since Faull's death -- but Telesforo Guerra, McAfee's lawyer in Guatemala, said the tactic was born out of necessity, not guilt.

"You don't have to believe what the police say," Guerra told ABC News. "Even though they say he is not a suspect they were trying to capture him."

Guerra, who is a former attorney general of Guatemala, said it would take two to three weeks to secure asylum for his client.

According to McAfee, Guerra is also the uncle of McAfee's 20-year-old girlfriend, Samantha. McAfee said the government raided his beachfront home and threatened Samantha's family.

"Fifteen armed soldiers come in and personally kidnap my housekeeper, threaten Sam's father with torture and haul away half a million dollars of my s***," claimed McAfee. "If they're not after me, then why all these raids? There've been eight raids!"

Before his arrest, McAfee said he would hold a press conference on Thursday in Guatemala City to announce his asylum bid. He has offered to answer questions from Belizean law enforcement over the phone, and denied any involvement in Faull's death.

Read More..

Chemical key to cell division revealed

In each of our cells, most of the genetic material is packaged safely within the nucleus, which is protected by a double membrane. The biochemistry behind how this membrane transforms when cells divide has finally been unravelled, offering insights that could provide new ways of fighting cancer and some rare genetic disorders.

During cell division, the membrane that surrounds the nucleus breaks down and reforms in the two daughter cells. Researchers have been split on the precise mechanisms that govern membrane reformation. One view is that proteins alone control the membrane's transformations. Another possibility is that changes in lipids – a vast group of fat-related compounds – are responsible.

Experiments had failed to show which of these two ideas was right, because it was difficult to alter lipid levels in specific compartments of cells without affecting other cellular processes.

Banafshe Larijani at Cancer Research UK's London Research Institute and her colleagues have now overcome that hurdle. They came up with a technique that transforms a type of lipid called a diacylglycerol (DAG) into another lipid, within the nuclear membrane.

Chemical cascade

The technique involves inserting two fragments of DNA into the nucleus of a cell. This causes the cell to make two proteins: the first attaches itself to the nuclear membrane, the second floats around the cell. Adding a drug – rapalogue – to the mix causes the second protein to stick to the first, which in turn causes a chemical cascade that transforms the DAG into a different kind of lipid.

Crucially, they targeted a form of DAG that does not bind to proteins, so converting it into a different lipid does not affect any processes involving proteins in the cell.

The team tested the effect of this lipid manipulation on cell division in monkey and human cancer cells. The lower the level of DAG present in the nuclear membrane, the greater the membrane malformation and chance of cell death.

This demonstrates that lipids play a role in nuclear membrane reformation that does not depend on proteins.

Larijani says it "opens the door to finding ways to kill cancerous cells" by focusing on lipids that are important to the nuclear membrane's development.

Sausage pieces

As the nucleus divides, sausage-shaped fragments of its membrane float around the cell. The fragments have curved ends, and Larijani says that changes in lipid composition generate these curves, without which the fragments cannot reassemble correctly into new membranes.

More than a dozen rare genetic conditions such as Hutchinson-Gilford progeria syndrome, which is characterised by premature ageing in children, have been linked to irregularities in cell division. A better understanding of the way the nuclear membrane forms when cells divide could be key to treating these disorders.

The research also offers a new focus for preventing the irregular cell division that underlies many cancers.

"As a result of this work we now know with confidence that DAG plays a structural role in membrane dynamics," says Vytas Bankaitis, at the Texas A&M Health Science Center in College Station, who was not involved in the study. "If we could find a molecule with suitable characteristics, this manipulation could be done [in humans], which is something that has not really been considered before."

Journal reference: PLoS ONE DOI: 10.1371/journal.pone.0051150

If you would like to reuse any content from New Scientist, either in print or online, please contact the syndication department first for permission. New Scientist does not own rights to photos, but there are a variety of licensing options available for use of articles and graphics we own the copyright to.

All comments should respect the New Scientist House Rules. If you think a particular comment breaks these rules then please use the "Report" link in that comment to report it to us.

If you are having a technical problem posting a comment, please contact technical support.

Read More..

Golf: Schwartzel takes early lead at Thailand championship

CHONBURI, Thailand: South Africa's Charl Schwartzel took an early lead at the Thailand Golf Championship with a seven-under-par 65 in the first round, energising his bid to avenge last year's second place to Lee Westwood.

The 2011 Masters champion hit seven birdies in steamy conditions at the Amata Spring course an hour outside Bangkok and hailed his fitness after a season dogged by injury.

"I'm just playing injury-free... that's allowing me to swing the club much better," he said, explaining his strong start to the Asian Tour event in which he came second last year to a rampant Westwood.

His form bodes well after a season where he has notched just two top 10 PGA Tour finishes, but the South African refused to get carried away with three days of golf in searing temperatures ahead.

"I played really well, I didn't miss many fairways... but you're not going to win after the first round, although you sure can lose it."

He took a one-shot clubhouse lead from home star Thitiphun Chuayprakong, with Spaniard Javi Colomo one more behind at five under.

Masters champion Bubba Watson, who had promised to showcase some of his famous buccaneering "Bubba Golf" in Thailand, carded a mixed round of four under.

It included a stirring run on the back nine of birdie, eagle, then birdie, which was undone by three bogeys in an error-strewn final six holes.

"It was a solid round but I made a few mistakes," said the lefthanded American.

"All of these guys are good players, it's the first day... it's going to be hot and we're going to have to stay focused," he said.

In a star-studded field American world number 25 Hunter Mahan was two under with five played, while defending champion Westwood - the highest ranked player at the event - had just started his round.

Westwood cruised to a seven-shot win at the inaugural event last year on the back of an opening round 12-under-par 60 - narrowly missing out on a magical 59, which has never been shot on the Asian Tour.

- AFP/de

Read More..

Apple returning to old stomping grounds for U.S.-made iMacs?

Some new iMacs, including the 21.5-inch iMac, are labeled as assembled in USA. Are they being made in Fremont, Calif.?

(Credit:
Apple)

Evidence suggests that Apple could be assembling some of the new iMacs in Fremont, Calif.

Two U.S. models that 9to5Mac traced originated in the San Jose area.

"One tipster's origination pickup point was briefly visible as Fremont CA so it would appear that
iMac assembly is happening in that general vicinity," the
Mac enthusiast site said.

Another possible location for an assembly operation would be Elk Grove, Calif., where Apple still has operations. But, so far, there's no hard evidence that units are being assembled there.

This follows images posted last week by iFixit showing "Designed by Apple in California, Assembled in USA" markings on the back of an iMac.

Fremont, of course, is where Apple made Macs back in the day and where Steve Jobs built a factory to manufacture the NeXT Computer.

But that was a long time ago in an era when companies like Compaq, IBM, Texas Instruments (yes, it used to make laptops) and Gateway assembled and/or manufactured PCs and PC components in the U.S.

So, Apple returning some of its assembly work to the U.S. would be an unexpected turn of events considering that pretty much anything computer related these days is made in Asia.

That said, Fremont has never been a stranger to large manufacturers. General Motors and Toyota jointly built
cars there for years. That NUMMI factory was eventually taken over by Tesla Motors, which now builds its electric cars there.

Apple has yet to respond to a request for comment.

2012 iMac balances beauty with brawn

Read More..

A 2020 Rover Return to Mars?

NASA is so delighted with Curiosity's Mars mission that the agency wants to do it all again in 2020, with the possibility of identifying and storing some rocks for a future sample return to Earth.

The formal announcement, made at the American Geophysical Union's annual fall meeting, represents a triumph for the NASA Mars program, which had fallen on hard times due to steep budget cuts. But NASA associate administrator for science John Grunsfeld said that the agency has the funds to build and operate a second Curiosity-style rover, largely because it has a lot of spare parts and an engineering and science team that knows how to develop a follow-on expedition.

"The new science rover builds off the tremendous success from Curiosity and will have new instruments," Grunsfeld said. Curiosity II is projected to cost $1.5 billion—compared with the $2.5 billion price tag for the rover now on Mars—and will require congressional approval.

While the 2020 rover will have the same one-ton chassis as Curiosity—and could use the same sky crane technology involved in the "seven minutes of terror"—it will have different instruments and, many hope, the capacity to cache a Mars rock for later pickup and delivery to researchers on Earth. Curiosity and the other Mars rovers, satellites, and probes have garnered substantial knowledge about the Red Planet in recent decades, but planetary scientists say no Mars-based investigations can be nearly as instructive as studying a sample in person here on Earth.

(Video: Mars Rover's "Seven Minutes of Terror.")

Return to Sender

That's why "sample return" has topped several comprehensive reviews of what NASA should focus on for the next decade regarding Mars.

"There is absolutely no doubt that this rover has the capability to collect and cache a suite of magnificent samples," said astronomer Steven Squyres, with Cornell University in New York, who led a "decadal survey" of what scientists want to see happen in the field of planetary science in the years ahead. "We have a proven system now for landing a substantial payload on Mars, and that's what we need to enable sample return."

The decision about whether the second rover will be able to collect and "cache" a sample will be up to a "science definition team" that will meet in the years ahead to weigh the pros and cons of focusing the rover's activity on that task.  

As currently imagined, bringing a rock sample back to Earth would require three missions: one to select, pick up, and store the sample; a second to pick it up and fly it into a Mars orbit; and a third to take it from Mars back to Earth.

"A sample return would rely on all the Mars missions before it," said Scott Hubbard, formerly NASA's "Mars Czar," who is now at Stanford University. "Finding the right rocks from the right areas, and then being able to get there, involves science and technology we've learned over the decades."

Renewed Interest

Clearly, Curiosity's success has changed the thinking about Mars exploration, said Hubbard. He was a vocal critic of the Obama Administration's decision earlier this year to cut back on the Mars program as part of agency belt-tightening but now is "delighted" by this renewed initiative.

(Explore an interactive time line of Mars exploration in National Geographic magazine.)

More than 50 million people watched NASA coverage of Curiosity's landing and cheered the rover's success, Hubbard said. If things had turned out differently with Curiosity, "we'd be having a very different conversation about the Mars program now."

(See "Curiosity Landing on Mars Greeted With Whoops and Tears of Jubilation.")

If Congress gives the green light, the 2020 rover would be the only $1 billion-plus "flagship" mission—NASA's largest and most expensive class of projects—in the agency's planetary division in the next decade. There are many other less ambitious projects to other planets, asteroids, moons, and comets in the works, but none are flagships. That has left some planetary scientists not involved with Mars unhappy with NASA's heavy Martian focus.

Future Plans

While the announcement of the 2020 rover mission set the Mars community abuzz, NASA also outlined a series of smaller missions that will precede it. The MAVEN spacecraft, set to launch next year, will study the Martian atmosphere in unprecedented detail; a lander planned for 2018 will study the Red Planet's crust and interior; and NASA will renew its promise to participate in a European life-detection mission in 2018. NASA had signed an agreement in 2009 to partner with the European Space Agency on that mission but had to back out earlier this year because of budget constraints.

NASA said that a request for proposals would go out soon, soliciting ideas about science instruments that might be on the rover. And as for a sample return system, at this stage all that's required is the ability to identify good samples, collect them, and then store them inside the rover.

"They can wait there on Mars for some time as we figure out how to pick them up," Squyres said. "After all, they're rocks."

Read More..

Guatemala Could Deport McAfee to Belize

Software anti virus pioneer John McAfee is in the process of being deported to Belize after he was arrested in Guatemala for entering the country illegally, his attorney told ABC News early Thursday.

ABC News has learned that John McAfee is scheduled to be deported to Belize later this morning. But a judge could stay the ruling if it is determined McAfee's life is threatened by being in Belizean custody, as McAfee has claimed over the past several weeks.

Just hours before McAfee's arrest, he told ABC News in an exclusive interview Wednesday he would be seeking asylum in Guatemala. McAfee was arrested by the Central American country's immigration police and not the national police, said his attorney, who was confident his client would be released within hours.

"Thank God I am in a place where there is some sanity," said McAfee, 67, before his arrest. "I chose Guatemala carefully."

McAfee said that in Guatemala, the locals aren't surprised when he says the Belizean government is out to kill him.
"Instead of going, 'You're crazy,' they go, 'Yeah, of course they are,'" he said. "It's like, finally, I understand people who understand the system here."

But McAfee added he has not ruled out moving back to the United States, where he made his fortune as the inventor of anti-virus software, and that despite losing much of his fortune he still has more money than he could ever spend.
In his interview with ABC News, a jittery, animated but candid McAfee called the media's representation of him a "nightmare that is about to explode," and said he's prepared to prove his sanity.

Johan Ordonez/AFP/Getty Images

Software Founder Breaks Silence: McAfee Speaks on Murder Allegations Watch Video

John McAfee Interview: Software Mogul Leaves Belize Watch Video

John McAfee Interview: Software Millionaire on the Run Watch Video

McAfee has been on the run from police in Belize since the Nov. 10 murder of his neighbor, fellow American expatriate Greg Faull.

During his three-week journey, said McAfee, he disguised himself as handicapped, dyed his hair seven times and hid in many different places during his three-week journey.

He dismissed accounts of erratic behavior and reports that he had been using the synthetic drug bath salts. He said he had never used the drug, and said statements that he had were part of an elaborate prank.

Investigators said that McAfee was not a suspect in the death of the former developer, who was found shot in the head in his house on the resort island of San Pedro, but that they wanted to question him.

McAfee told ABC News that the poisoning death of his dogs and the murder just hours later of Faull, who had complained about his dogs, was a coincidence.

McAfee has been hiding from police ever since Faull's death -- but Telesforo Guerra, McAfee's lawyer in Guatemala, said the tactic was born out of necessity, not guilt.

"You don't have to believe what the police say," Guerra told ABC News. "Even though they say he is not a suspect they were trying to capture him."

Guerra, who is a former attorney general of Guatemala, said it would take two to three weeks to secure asylum for his client.

According to McAfee, Guerra is also the uncle of McAfee's 20-year-old girlfriend, Samantha. McAfee said the government raided his beachfront home and threatened Samantha's family.

"Fifteen armed soldiers come in and personally kidnap my housekeeper, threaten Sam's father with torture and haul away half a million dollars of my s***," claimed McAfee. "If they're not after me, then why all these raids? There've been eight raids!"

Before his arrest, McAfee said he would hold a press conference on Thursday in Guatemala City to announce his asylum bid. He has offered to answer questions from Belizean law enforcement over the phone, and denied any involvement in Faull's death.

Read More..

When is a baby too premature to save?

It was never easy, but trying to decide whether to save extremely premature babies just got harder.

A study called EPICure compared the fates of babies born 22 to 26 weeks into pregnancy in the UK in 1995 with similar babies born in 2006. In this 11-year period, the babies surviving their first week rose from 40 to 53 per cent. But an accompanying study comparing the fate of survivors at age 3 found that the proportion developing severe disabilities was unchanged, at just under 1 in 5.

"We've increased survival, but it's confined to the first week of life," says Kate Costeloe of Queen Mary, University of London, author of the first study. "Yet the pattern of death and health problems is strikingly similar between the two periods."

The absolute numbers of premature babies born over the 11 year period increased by 44 per cent, from 666 in 1995 to 959 in 2006. This meant that the absolute numbers of children with severe disabilities such as blindness, deafness or lameness also rose, increasing the burden on health, educational and social services.

Lifelong disability

"As the number of children that survive preterm birth continues to rise, so will the number who experience disability throughout their lives," says Neil Marlow of University College London, who led the second study.

By far the worst outcomes were for the youngest babies, with 45 per cent of those born at 22 or 23 weeks in 2006 developing disabilities compared with 20 per cent of those born at 26 weeks. In 1995 only two babies survived after being born at 22 weeks. In 2006, three did.

In 2006, a panel of UK ethicists concluded that babies born at 22 weeks should be allowed to die, as with babies born at or before 23 weeks in France and Holland.

Journal references: BMJ, Costeloe et al, DOI: 10.1136/bmj.e7976; Marlow et al, DOI: 10.1136/bmj.e7961

If you would like to reuse any content from New Scientist, either in print or online, please contact the syndication department first for permission. New Scientist does not own rights to photos, but there are a variety of licensing options available for use of articles and graphics we own the copyright to.

All comments should respect the New Scientist House Rules. If you think a particular comment breaks these rules then please use the "Report" link in that comment to report it to us.

If you are having a technical problem posting a comment, please contact technical support.

Read More..

Golf: Rose, Scott to face off at Australian Open

SYDNEY: England's Justin Rose and Adam Scott of Australia will face off in a pairing in the opening two rounds of the Australian Open, teeing off at The Lakes in Sydney on Thursday.

Rose and Scott are the top drawcards at the A$1.25 million ($1.3 million) tournament but the spotlight will also be on Chinese teen sensation Guan Tianlang - the youngest player ever to qualify for the US Masters.

World number four Rose, who finished second behind top-ranked Rory McIlroy at last month's World Tour Championship in Dubai, will play the opening 36 holes alongside Scott, seventh in the rankings.

"It is a great draw for me. I regard Adam as one of my best friends out on Tour," Rose said on Wednesday.

"The great thing is that you play the golf course. You are not really eye-to-eye or head-to-head, especially on days one and two."

Scott beat England's Ian Poulter by four shots at Melbourne's Kingston Heath last month to win the Australian Masters for the first time, saying it made up "in a small way" for his capitulation at this year's British Open, when he blew a four-shot lead over the last four holes at Royal Lytham.

The top-ranked Australian said he will probably use his broomstick putter as he chases a second Australian Open crown at the event, co-sanctioned by the PGA Tour of Australasia and OneAsia.

Scott played his practice round at The Lakes on Tuesday without his trusty long putter.

"I'll probably putt with the long putter," he said on Wednesday.

"The other one I was messing around with was my first go and it's not quite what I wanted. It is not quite set up right for me.

"I'll have another go at another time if I feel I need to."

World golf's two law-making bodies, the R&A and USGA, have proposed to outlaw "anchored" putting, where the club is pivoted by a player's belly or chest, by 2016.

Chinese phenomenon Guan, 14, plans to use the Australian experience as preparation for his appearance at the US Masters in April.

"I think (it will be good preparation for the Masters) because it's a pretty big tournament," said Guan, who won last month's Asia-Pacific Amateur Championship.

"To play with some of the world's greatest players, I want to enjoy everything about it - the course and all the stuff they do. Just get to know all about it," he added.

Tom Watson, the eight-time Major winner who is also playing in Sydney, said there was a chance that Guan would not fulfil his potential although he did not think that would be the case.

"This young man has been cultured into golf. I've read some of his history. Golf is his life. We have seen a lot of golf prodigies, many of whom did not make it. Is there a danger of that? Yes, there is.

"But if I had that chance at 14, I'd jump at it. I'd be at Augusta quicker than you could spit."

Australian left-hander Greg Chalmers is defending his Australian Open title.

- AFP/de

Read More..

Redbox Instant's full launch won't be until spring 2013

It looks like the rumor mill was a little off this time -- Verizon's Redbox Instant won't be launching this month, as was previously speculated but rather in 2013. However, its public beta should be good to go within the next few weeks.

Verizon chairman and CEO Lowell McAdam announced today at an investor conference that after public beta testing the commercial launch of the video streaming and DVD rental service should kick off either at the end of 2013's first quarter or the beginning of the second quarter, according to The Hollywood Reporter.

"We are in the process of internal employee beta testing right now and we are very pleased with the progress," McAdam said at the conference. "I think later this month into the first part of January, we will open it up to customers but in a beta sort of format so that we can shake out any kinks that are left in the process."

Redbox Instant is a joint venture that was announced in February between Verizon and Coinstar -- the company that owns the Redbox DVD rental business. The companies have worked on developing an on-demand video streaming service with DVD rentals, much like what Netflix offers. They had originally expected to introduce the new service in the second half of 2012.

Read More..

Scientific Results From Challenger Deep

Jane J. Lee

The spotlight is shining once again on the deepest ecosystems in the ocean—Challenger Deep in the Mariana Trench (map) and the New Britain Trench near Papua New Guinea. At a presentation today at the American Geophysical Union's conference in San Francisco, attendees got a glimpse into these mysterious ecosystems nearly 7 miles (11 kilometers) down, the former visited by filmmaker James Cameron during a historic dive earlier this year.

Microbiologist Douglas Bartlett with the University of California, San Diego described crustaceans called amphipods—oceanic cousins to pill bugs—that were collected from the New Britain Trench and grow to enormous sizes five miles (eight kilometers) down. Normally less than an inch (one to two centimeters) long in other deep-sea areas, the amphipods collected on the expedition measured 7 inches (17 centimeters). (Related: "Deep-Sea, Shrimp-like Creatures Survive by Eating Wood.")

Bartlett also noted that sea cucumbers, some of which may be new species, dominated many of the areas the team sampled in the New Britain Trench. The expedition visited this area before the dive to Challenger Deep.

Marine geologist Patricia Fryer with the University of Hawaii described some of the deepest seeps yet discovered. These seeps, where water heated by chemical reactions in the rocks percolates up through the seafloor and into the ocean, could offer hints of how life originated on Earth.

And astrobiologist Kevin Hand with the Jet Propulsion Laboratory in Pasadena, California, spoke about how life in these stygian ecosystems, powered by chemical reactions, could parallel the evolution of life on other planets.

Read More..